Biomolecules

Aspartame, an artificial sweetener, is a dipeptide aspartyl phenylalanine methyl ester. The structure of aspartame is

(Structures of phenylalanine and aspartic acid are given below.)

In the following reaction sequence, the major product Q is

$$\text{L-Glucose} \xrightarrow[\text{ii) } \ce{Cr2O3},\ 775\,\mathrm{K},\ 10\text{-}20\,\mathrm{atm}]{\text{i) HI},\ \Delta} \mathbf{P} \xrightarrow[\text{UV}]{\ce{Cl2}\ \text{(excess)}} \mathbf{Q}$$

For a double strand DNA, one strand is given below:

$$5'\text{-A G T C A C G T A A G T C-}3'$$

The amount of energy required to split the double strand DNA into two single strands is _____ $\mathrm{kcal\,mol^{-1}}$.

[Given: Average energy per H-bond for A-T base pair $= 1.0\,\mathrm{kcal\,mol^{-1}}$, G-C base pair $= 1.5\,\mathrm{kcal\,mol^{-1}}$, and A-U base pair $= 1.25\,\mathrm{kcal\,mol^{-1}}$. Ignore electrostatic repulsion between the phosphate groups.]

A disaccharide X cannot be oxidised by bromine water. The acid hydrolysis of X leads to a laevorotatory solution. The disaccharide X is

Considering the reaction sequence given below, the correct statement(s) is(are)

Treatment of D-glucose with aqueous NaOH results in a mixture of monosaccharides, which are

A polysaccharide 'X' on boiling with dil $\mathrm{H_2SO_4}$ at 393 K under 2-3 atm pressure yields 'Y'. 'Y' on treatment with bromine water gives gluconic acid. 'X' contains $\beta$-glycosidic linkages only. Compound 'X' is :

In alanylglycylleucylalanylvaline, the number of peptide linkages is ______.

Match List I with List II.

Choose the correct answer from the options given below:

A protein 'A' contains 0.30% of glycine (molecular weight 75). The minimum molar mass of the protein 'A' is ______ $\times10^3$ g mol$^{-1}$ [nearest integer]

How many of the given compounds will give a positive Biuret test ______ ?

Glycine, Glycylalanine, Tripeptide, Biuret

The number of oxygens present in a nucleotide formed from a base, that is present only in RNA is ______.

Match List I with List II.

Choose the most appropriate answer from the options given below:

Which one of the following is a water soluble vitamin, that is not excreted easily?

L-isomer of a compound 'A' ($\mathrm{C_4H_8O_4}$) gives a positive test with $\mathrm{[Ag(NH_3)_2]^+}$. Treatment of 'A' with acetic anhydride yields triacetate derivative. Compound 'A' produces an optically active compound (B) and an optically inactive compound (C) on treatment with bromine water and $\mathrm{HNO_3}$ respectively. Compound (A) is :

Given below are two statements.

Statement I: Maltose has two $\alpha$-D-glucose units linked at $C_1$ and $C_4$ and is a reducing sugar.

Statement II: Maltose has two monosaccharides: $\alpha$-D-glucose and $\beta$-D-glucose linked at $C_1$ and $C_6$ and it is a non-reducing sugar.

In the light of the above statements, choose the correct answer from the options given below.

Stability of $\alpha$ - Helix structure of proteins depends upon

When sugar 'X' is boiled with dilute $\mathrm{H_2SO_4}$ in alcoholic solution, two isomers 'A' and 'B' are formed. 'A' on oxidation with $\mathrm{HNO_3}$ yields saccharic acid where as 'B' is laevorotatory. The compound 'X' is :

2.5 g of protein containing only glycine ($\mathrm{C_2H_5NO_2}$) is dissolved in water to make 500 mL of solution. The osmotic pressure of this solution at 300 K is found to be $5.03\times10^{-3}$ bar. The total number of glycine units present in the protein is ______.

(Given : R = 0.083 L bar K$^{-1}$ mol$^{-1}$)

Sugar moiety in DNA and RNA molecules respectively are